Postdoctoral Research Associate
Position Number: 00106471
Essential Job Duties: Understanding the mechanistic basis of addiction will have considerable impact on our ability to stem the rising epidemic in substance abuse disorders. Powerful animal models and genetic tools have provided important insights over the past several decades. However, there are several important challenges that remain in our understanding of addiction. In particular, while considerable effort has been spent understanding the genetic basis of addiction, the role of the epigenome and chromatin is unclear. Chromatin is the collection of RNAs and proteins bound to genomic DNA that regulate the expression of genetic information. The primary purpose of this project is to develop a deeper understanding of chromatin's role in substance abuse and in reward pathways in general. Towards the project's primary goal, sub-aims are to develop molecular tools to perturb and interface with chromatin and to develop cellular and multicellular addiction models derived from human stem cells. The techniques and tools this position will develop and implement include high through-put molecular biology, biochemical assays such as ChIP, mammalian and microbial cell culture, flow cytometry, confocal microscopy, neurobiology, and systems biology.
Department Required Skills: PhD in molecular biology, neuroscience, biochemistry, bioengineering, biomedical engineering, or chemical engineering at time of hire.
Preferred Experience, Skills, Training/Education: PhD. Previous experience with synthetic biology, neuroscience, stem cells, molecular biology, chromatin biology is encouraged.
Necessary Licenses and Certifications: N/A
AA/EOE: NC State University is an equal opportunity and affirmative action employer. All qualified applicants will receive consideration for employment without regard to race, color, national origin, religion, sex, gender identity, age, sexual orientation, genetic information, status as an individual with a disability, or status as a protected veteran.
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