Laboratory Specialist

Charlottesville, VA
Jul 14, 2017
Institution Type
Four-Year Institution

Working Title: Laboratory Specialist

Position Type: University Operational and Administrative Staff

Department: Department of Biochemistry and Molecular Genetics

Location: Charlottesville

Posting Date: 07-13-2017

Posting Summary:
The Adli lab in the Department of Biochemistry & Molecular Genetics at the University of Virginia is seeking a Laboratory Specialist to perform and assist computational biologists and experimentalists for their data analysis. The candidate may also help to maintain laboratory space, equipments and servers as well as process purchases for the lab. In this role, the candidate will particularly help senior computational biologist to analyze and interpret high-throughput genomic data from whole-genome sequencing, ChIP-seq, RNA-seq and single cell RNA-Seq data to formulate or test specific hypothesis.

The Adli lab ( is using genomic and epigenomic mapping, manipulating as well as imaging approaches to understand how external (developmental and environmental cues) and internal (genetic abnormalities) cues alter gene regulation, chromatin structure, and the 3D genome organization in the nuclear space. In addition to using conventional genomic and epigenomic approaches, the lab is also exploiting its existing expertise in CRISPR technology (Nature Biotechnology, 2014; NAR, 2015) to develop and use CRISPR-based next-generation locus specific chromatin manipulation and imaging (Nature Communications, 2017) as well as catalytically inactive Cas9 based gene silencing through base editing (Nature Methods, 2016; Nature Methods, 2017) technologies. The current proposal is based on our recent exciting preliminary results and long-term interest in understanding the role of nuclear lamina and its associated proteins in genome architecture and gene regulation.

Position requires a bachelor's degree in a science-related field with a minimum of three years of laboratory experience, preferably in an academic laboratory setting. Student experience may be considered. Incumbent may be required to assist the Principle Investigator with the supervision of the work of graduate students and assist senior staff with areas of need.

This position is restricted and contingent upon the continuation of funding.

Required Knowledge, Skills and Abilities:
1. Knowledge of routine laboratory procedures, including surgical and experimentation.
2. Ability to obtain and record data.
3. Ability to prepare solutions or reagents.
4. Ability to analyze data.
5. Excellent written and verbal communications skills.
6. Ability to work with animals.

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