Professional Research Assistant

Location
Aurora, CO
Posted
Jul 07, 2017
Institution Type
Four-Year Institution



University of Colorado - School of Medicine

Professional Research Assistant



Nature of Work:

The selected candidate will be responsible for performing cell processing and testing at the newly established Gates Biomanufacturing Facility to meet client and cGMP requirements for the manufacture, testing, and distribution of cell-based products for patient administration.

Professional Field:

This position requires experience related to performing aseptic cell culture and Cell Therapy product analyis.

Supervision Received:

This position reports directly to the Director of Cell Therapies at the Gates Biomanufacturing Facility.

Examples of Work Performed:

  • Full-time position at the Gates Biomanufacturing Facility located nearby the University of Colorado Anschutz Medical Campus.
  • Perform cell characterization and cell-based assays on a routine basis using techniques such as flow cytometry, quantitative real-time PCR, immunostaining, fluorescence cell imaging, ELISA, and fluorescence/luminescence microplate-based assays.
  • Develop and implement new analytical test methods for characterization testing of cell-based products.
  • Analyze samples and interpret results. Perform calculations and statistical analysis to complete research test results.
  • Development and implementation of startup operations and SOPs at the new facility to meet client and cGMP requirements for cell-based products.
  • Perform aseptic cell culture processing on a routine basis.
  • Development and implementation of process development screening and optimization experiments of cell-based products.
  • Maintain laboratory notebooks, logs, and computer databases.
  • Compile information and results into meaningful formats to ensure content is appropriately represented. This may involve presenting the information to clients.
  • Manage, monitor and maintain processing and testing equipment, facilities, and supplies. This will include routine handling and lifting of laboratory supplies, and bench-top equipment and regular cleaning of facility, supplies, and equipment.
  • Perform calibration, verification, and qualification of equipment, processes, and test methods.
  • Manage projects and tasks to meet project expectations related to timelines, budget, and quality.
  • Implement continual quality and process improvement processes within the development and manufacturing phases of a product.
  • Long-term, train new staff in cell therapy processes to achieve operational, schedule, and quality requirements.
  • Long-term, employee could develop laboratory techniques related to the development, manufacturing, and analytical testing of therapeutic proteins produced at this facility.
  • Provide exceptional customer service to users of the facility.
  • Work in a professional and collaborative manner with coworkers and prospective users. Due to manufacturing schedule, nights and weekends may be required for hours worked.


Salary and Benefits:



Salary is commensurate with skills and experience. The University of Colorado offers a full benefits package. Information on University benefits programs, including eligibility, is located at Employee Services.

The University of Colorado Denver is dedicated to ensuring a safe and secure environment for our faculty, staff, students and visitors. To assist in achieving that goal, we conduct background investigations for all prospective employees.

The University of Colorado strongly supports the principle of diversity. We encourage applications from women, ethnic minorities, persons with disabilities and all veterans. The University of Colorado is committed to diversity and equality in education and employment.

The Immigration Reform and Control Act requires that verification of employment eligibility be documented for all new employees by the end of the third day of work. Alternative formats of this ad are available upon request for persons with disabilities.


Qualifications

Knowledge, Skills, and Abilities:

  • Experience with flow cytometry, qRT-PCR, ELISA, cell-based assays, ELISAs, fluorescence/luminescence microplate assays, cell viability assays, and fluorescence microscopy.
  • Experience performing aseptic cell culture.
  • Experience working in a start-up environment with a track record of being a team-oriented, self-starter capable of operating independently.
  • Experience operating and maintaining cell/tissue culture and analytical equipment.
  • Experience isolating and establishing cell lines from tissues.
  • Experience with managing databases.
  • Knowledge of statistical analyses is beneficial.
  • Experience with image analysis software.


Minimum Requirements:

  • Bachelor's Degree or equivalent experience in Cell Biology, Bioengineering, Chemical Engineering, or related field.
  • At least 1 year of experience related to general tissue/cell culture.
  • At least 2 years of experience performing research in an academic setting.


Preferred Qualifications:

  • Master's Degree or equivalent experience in Cell Biology, Bioengineering, Chemical Engineering, or related field.
  • At least 1 year of experience specifically related to performing aseptic cell culture for a variety of human-derived cell populations.
  • Experience working in a cGMP manufacturing setting related to biological drugs intended for human use.
  • Experience working with FDA and ISO regulations.
  • Experience writing applications for IRB approval.




Application Materials Required:Cover Letter, Resume/CV, List of References

Application Materials Instructions:

Applications are accepted electronically at CU Careers, refer to requisition ID: 10094

When applying, applicants must include:
  1. A letter of application which specifically addresses the job requirements and outlines qualifications
  2. A current Resume/CV
  3. The names, addresses, daytime telephone numbers and e-mail addresses for three professional references, either attached to your resume/CV or uploaded as a separate document
Please be advised that the University does check references as part of the employment process.

Please do not submit any of your application material (via email) to the job posting contact.



Job Category: Faculty

Primary Location: Aurora

Department: H0001 -- Anschutz Medical Campus - 20143 - SOM-Dermatology

Schedule: Full-time

Posting Date: Jul 6, 2017

Closing Date: Ongoing

Posting Contact Name: Matthew Seefeldt

Posting Contact Email: matthew.seefeldt@ucdenver.edu

Position Number: 00050259

PI98546417