Research Scientist

Charlottesville, VA
Jul 05, 2017
Institution Type
Four-Year Institution

Working Title: Research Scientist

Position Type: Professional Research Staff

Department: Department of Biochemistry and Molecular Genetics

Location: Charlottesville

Posting Date: 03-06-2017

Posting Summary:
The Department of Biochemistry and Molecular Genetics at the University of Virginia seeks a senior molecular biologist or biochemist for a new Research Scientist position. The candidate will work in the Adli lab and will independently develop CRISPR-assisted knock-in strategies to rapidly deplete chromatin regulators and lamina-associated proteins to better understand their roles in 3D and 4D genome organization and gene regulation. The candidates expected to be academically independent and have deep expertise in cloning and single cell analysis.

About the Adli Lab: Our group is at the interface of experimental and computational genomic approaches. We utilize a wide range of molecular biology tools and sophisticated computational biology approaches to better understand the regulation of genome in normal and malignant development. We develop and adopt CRISPR-based experimental techniques to study basic mechanisms of chromatin function within the context of cancer biology (Kuscu et al., Nature Biotechnology, 2014; Singh et al., NAR, 2015; Kuscu et al., Nature Methods, 2016; Qi et al., Nature Communications, 2017). Visit our website:

Candidates must have a Ph.D. or equivalent degree in Molecular Biology, Biochemistry, Cell Biology, Biomedical Science, Development, Genomics, or a related field in hand by start date, as well as at least five years of postdoctoral experience that resulted in lead author papers. A strong interest in at least one of the following is required: transcription factors, transcription regulatory networks; chromatin; cancer biology. The successful candidate must be self-motivation and possess time management skills, and be independent, creative, and have a passion for science. Familiarity with the transcription and genomics literature is preferred, as is experience with analyzing genomics data, and a record of publication in peer-reviewed journals.

To apply, visit and search on Posting Number 0620448. Complete a Candidate Profile online, attach a cover letter, curriculum vitae, and contact information for three references. The position will remain open until filled.

For additional information about the position and application process, please contact Helen Norfleet-Shiflett via email

The University of Virginia is an affirmative action/equal opportunity employer committed to diversity, equity, and inclusiveness. Women, minorities, veterans, and persons with disabilities are strongly encouraged to apply.

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