Life Science Research Professional 1

Location
Stanford
Posted
May 17, 2017
Institution Type
Four-Year Institution


Stanford University

Life Science Research Professional 1

Job Number:
74957

Note: Not all unique aspects of the job are covered by this job description

JOB PURPOSE:


The Department of Biology is seeking a 100% full-time Life Science Research Professional (LSRP) 1 starting June 1, 2017 to work with a group of postdocs, graduate students and undergraduates to help understand how neurons, specifically axons respond to trophic deprivation and injury. We wish to uncover the molecular basis and therefore the mechanisms underlying axonal degeneration and neuron cell death with the goal of developing therapies for traumatic brain injury and neurodegenerative disease. We are seeking a LSRP to perform basic functions and activities involved in a defined research project and to independently conduct and analyze experiments. The LSRP will work as part of a team focused on research related to in vitro cell-based models and in vivo mouse models of neural development and neurodegeneration.


The group is looking for a LSRP1 who is interested in neuroscience research grounded in molecular biology, biochemistry and basic neurobiology. Specifically, we are trying to find permissive factors required for destruction of axons in a caspase dependent manner. We have conducted a large-scale mass spectrometry screen to identify factors downstream of caspase activated axon degeneration are characterizing the hits. Specifically, we would like a 100% LSRP1 to perform basic functions and activities involved in defined research projects and independently conduct and analyze experiments.


An ideal candidate would be proficient in molecular cloning, site-directed mutagenesis, lentiviral production and ideally would have experience in culturing primary neurons. Additional useful skills would be bioinformatics skills and coding (python). We are looking for a LSRP1 who has demonstrated an aptitude for science and wants to pursue these goals by conducting self-directed research projects. Responsibilities include, but are not limited to: 1) primary and immortalized cell culture, including lentiviral production 2) animal husbandry (e.g. breeding, genotyping), 3) molecular biology (e.g. Western blotting, immunostaining, qPCR, DNA subcloning).


Additional day-to-day lab functions include ordering supplies, and maintaining lab stocks. Applicant should be organized, detail-oriented, intellectually motivated and have excellent communication skills. LSRP will be involved in a defined research project with moderate supervision. Strong references that document prior research experience and skills are required. Salary commensurate with experience.

The LSRP will report to the Lab Manager/Principal Investigator and may be responsible for supervising Life Science Technicians.


Strong references that document prior research experience and skills are required. Salary commensurate with experience.

Weekend work may be necessary at times. Required weekend work can be substituted for normal workday hours. Work will be carried out primarily in the Department of Biology in Gilbert labs but will require visits to the animal facility, other core facilities and collaborating labs.

CORE DUTIES*:

  • Plan and perform experiments in support of research projects in lab and/or field based on knowledge of scientific theory. Interpret and perform basic analyses of results.

  • Review literature on an ongoing basis to remain current with new procedures and related research.

  • Offer suggestions regarding modifications to procedures and protocols in collaboration with graduate post-doctoral individuals.

  • Maintain detailed records of experiments and outcomes.

  • Contribute to publication of findings as needed. Participate in the preparation of written documents, including procedures, presentations, and proposals.

  • Help with general lab maintenance as needed; maintain lab stock, manage chemical inventory and safety records, and provide general lab support as needed.

  • Help orient and train new staff or students.

    * - Other duties may also be assigned

    MINIMUM REQUIREMENTS:


    Education & Experience:


    Bachelor's degree in related scientific field.


    Preferred Education & Experience:


    The candidate should have a B.A. or B.S. or Masters in Biology, Biochemistry, or a related field, and at least 1-3 years of experience in a relevant laboratory setting, preferably with experience in histology and neuroscience techniques as well as in the culture of cell lines. An advanced degree is strongly preferred. They must be able to work closely, yet independently with other lab members. Exceptional organizational abilities, and attention to detail are required.


    Knowledge, Skills and Abilities:

  • General understanding of scientific principles.

  • Experience working with immortalized cells, specifically making lentivirus and analysis by western blot

  • General computer skills and ability to quickly learn and master computer programs, databases, and scientific applications.

  • Ability to work under deadlines with general guidance.

  • Excellent organizational skills and demonstrated ability to accurately complete detailed work.

    Certifications and Licenses:

    None


    PHYSICAL REQUIREMENTS*:

  • Frequently stand, walk, twist, bend, stoop, squat, grasp lightly, use fine manipulation, grasp forcefully, perform desk-based computer tasks, use telephone, write by hand, lift, carry, push and pull objects weighing over 40 pounds.

  • Occasionally sit, kneel, crawl, reach and work above shoulders, sort and file paperwork or parts.

  • Rarely climb, scrub, sweep, mop, chop and mix or operate hand and foot controls.

  • Must have correctible vision to perform duties of the job.

  • Ability to bend, squat, kneel, stand, reach above shoulder level, and move on hard surfaces for up to eight hours.

  • Ability to lift heavy objects weighing up to 50 pounds.

  • Ability to work in a dusty, dirty, and odorous environment.

  • Position may require repetitive motion.

    * - Consistent with its obligations under the law, the University will provide reasonable accommodation to any employee with a disability who requires accommodation to perform the essential functions of his or her job.


    WORKING CONDITIONS:

  • May require working in close proximity to blood borne pathogens.

  • May require work in an environment where animals are used for teaching and research.

  • Position may at times require the employee to work with or be in areas where hazardous materials and/or infectious diseases are present.

  • Employee must perform tasks that require the use of personal protective equipment, such as safety glasses and shoes, protective clothing and gloves, and possibly a respirator.

  • May require extended or unusual work hours based on research requirements and business needs.

    WORK STANDARDS:

  • Interpersonal Skills: Demonstrates the ability to work well with Stanford colleagues and clients and with external organizations.

  • Promote Culture of Safety: Demonstrates commitment to personal responsibility and value for safety; communicates safety concerns; uses and promotes safe behaviors based on training and lessons learned.

    Subject to and expected to comply with all applicable University policies and procedures, including but not limited to the personnel policies and other policies found in the University's Administrative Guide, http://adminguide.stanford.edu.

    Stanford is an equal opportunity employer and all qualified applicants will receive consideration without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, veteran status, or any other characteristic protected by law.


    Final offers of employment are contingent upon successful completion of national criminal background check, national sex offender registry search and, where applicable, driving record.



    Job: Research

    Location: School of Humanities and Sciences
    Schedule: Full-time
    Classification Level:

    To be considered for this position please visit our web site and apply on line at the following link: stanfordcareers.stanford.edu

    Stanford is an equal opportunity employer and all qualified applicants will receive consideration without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, veteran status, or any other characteristic protected by law.






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