RESEARCH SPECIALIST A
Duties: The candidate will work in the High-Throughput Screening Core (HTSC) in the Perelman School of Medicine (PSOM). He/she will work with the Scientific and Technical Directors of the core to further design, to optimize and validate biological assays in high-density formats (i.e. 384 well microtiter plates) for primary human cancers that can be screened against libraries of FDA approved drugs, as part of a collaborative research initiative between the Chemogenomic Discovery Program, Precision Medicine, and Hospital of University of Pennsylvania. The candidate will also dedicate effort to high-throughput cell based screens designed to dissect the role of epigenetics in cellular senescence. Specific responsibilities will include moderately complex procedures/techniques in eukaryotic/mammalian cell-culture, molecular biology, cell biology, and high-throughput genetic/chemical screening. The candidate will operate and maintain automated laboratory robotic workstations related to high-throughput screening; prepare and manage libraries of siRNA, shRNA, cDNA, CRISPR and drug-like small molecule libraries for high-throughput screening; and analyze, interpret, and prepare reports of large data sets. Additional responsibilities will include literature searches, maintaining articulate documentation of daily tasks and maintenance of the laboratory's databases/logs and inventory (i.e. supplies, reagents, and equipment).
Position is contingent on continued funding.
Qualifications: A Bachelor's Degree and 0 to 1 year of experience or equivalent combination of education and experience is required. 1 to 3 years of experience preferred.
The ideal candidate will have strong organizational skills, effective communication skills; and the ability to problem-solve and work independently. The applicant should have basic understanding of cell biology, molecular biology and biochemistry. Experience in bioinformatics and programming is desirable.
Reference Number: 40-25764
Salary Grade: 024
Employment Type: Exempt
Special Requirements: Background check required after a conditional job offer is made. Consideration of the background check will be tailored to the requirements of the job.
Job Family: I-Technical/Professional Research