Research Associate

Location
Worcester, MA
Posted
May 11, 2017
Institution Type
Four-Year Institution
GENERAL SUMMARY OF POSITION:

Under the direction of the Principal Investigator or Designee, the Research Associate performs a variety of complex research experiments.

We are seeking a highly motivated individual to join a dynamic research team in the area of pluripotent stem cell biology. The Research Associate will apply cutting edge CRISPR technologies in human pluripotent stem cells and closely interact with other lab members to design and execute (epi-)genome editing projects. The individual will learn and apply human pluripotent stem cells and CRISPR technologies as well as molecular biology and epigenomics approaches. The ideal candidate will have a strong background in cell culture and molecular biology.

This lab focuses on combining stem cell biology and immunology to understand human immune syndromes, including Type 1 Diabetes. We develop and study human pluripotent stem cell-based disease models. In this role you will assist pluripotent stem cell studies under guidance of the principle investigators or designee.

Other responsibilities include-

    Propagation and maintenance of human pluripotent stem cells Molecular Biology to support plasmid generation and characterization of cells Basic cell biology (immunofluorescence microscopy) to support cell characterization Testing and troubleshooting new methods and equipment Maintain meticulous records and organize cell lines and reagents Work closely in a team setting with other scientists to coordinate experiments

MAJOR RESPONSIBILITIES:

  • Conducts in-depth analysis of research experiments
  • Performs complex laboratory experiments
  • Interprets data, forms conclusion, and decides on and plans next experiments to be done with a high degree of independence
  • Compiles and analyzes data and performs computations using image analysis software, spreadsheets, graphing, and curve fitting software
  • May modify protocols and be responsible for a single, independent research project
  • Assists in writing the text of scientific publications and grants. Reviews literature
  • Trains new laboratory personnel, students, and collaborators
  • Maintains laboratory supplies and equipment
  • Complies with all safety and infection control standards
  • Perform other duties as required.


REQUIRED QUALIFICATIONS:

  • Bachelor's degree in Biological Sciences, or equivalent experience
  • 1 year relevant research experience
  • Knowledge of Microsoft Office products
  • Strong ability to analyze complex visual data in a quantitative and objective manner
  • Judgment and action skills required to solve commonly encountered problems
PREFERRED QUALIFICATIONS:

    BA/BS and research experience including molecular biology and tissue culture Excellent communication, organizational and computer skills are essential Excellent understanding of molecular biology skills in the areas of DNA and RNA processing, and tissue culture skills Tissue culture experience or experience with CRISPR technology Attention to detail
SUPERVISION RECEIVED:

Under the direction of the Principal Investigator, or designee

SUPERVISION EXERCISED:

May functionally supervise Lab Technicians and Aides

ENVIRONMENTAL WORKING CONDITIONS:

Wet chemistry laboratory, and may require appropriate contact with biohazards, radionuclides, toxins, animals, and human specimens.

PI97817827