Research Specialist 1

May 06, 2017
Institution Type
Four-Year Institution
About The Unit: Dr. Mark Applebaum is a member of the section of Hematology/ Oncology & Stem Cell Transplantation in the Department of Pediatrics. The long-term focus of his laboratory research is focused on understanding the biology of neuroblastoma and to translate laboratory findings into clinical use. The principle contribution of this position is providing technical and administrative support in an exciting research program designed to understand the fundamental mechanisms of the hypoxia response in neuroblastoma and to develop new therapeutic strategies to combat therapeutic resistance. The laboratory uses cell culture and mouse models to recapitulate human disease with a clear goal for clinical translation. The laboratory is looking for a bright, meticulous, motivated, and curious individual who would like to learn about translational medicine and master an array of biomedical techniques.

Unit Job Summary: Under the direction of the principal investigator, will work as a proactive participant with a team of researchers investigating the biology of neuroblastoma. Laboratory-related responsibilities include performing moderately complex lab and research-related duties and tasks. Specific laboratory skills include maintenance of human cancer cell lines, cell death and proliferation assays, flow cytometry, PCR, real-time PCR, plasmid preparations, western blots, in vitro drug testing, immunohistochemical and immunofluorescent staining, light-field/fluorescent microscopy, and basic molecular biology techniques. Animal studies include small animal procedures such as subcutaneous injections, oral and IP drug administration, necropsies, and preparation of samples for histologic examination. As an important part of scientific research, one will be expected to analyze data, conduct literature reviews, assist with preparation of reports, manuscripts and other documents. Additional responsibilities would include maintaining and ordering equipment and supplies. May work, orient, or coordinate with other research support staff and students. Responsibilities may include the following non-laboratory duties: assisting with developing data collection tools, assisting with building databases, and providing general administrative support. The requested position is critical to be filled to assist Dr. Mark Applebaum, who has recently been appointed as Physician Scientist, with research and related laboratory and non-laboratory duties. The position will become vacant effective July 21, 2017 and there are no additional laboratory staff currently working with Dr. Applebaum or with capacity to take on additional duties. If this position is not filled, Dr. Applebaum will be unable to continue research that is supported by NIH grant and recruitment package funding; data gathering and small animal procedure needs will go unmet, and there will be an adverse delay in achieving goals set forth in the study proposalmeeting deadlines, completion of the study and publication findings per approved timelines.

Unit Education: Bachelor's degree in a field relevant to the research being conducted, required.

Unit Experience: One year relevant research experience, preferred. Experience with basic molecular biology techniques, preferred. Willing to work with mice, preferred.

Unit Job Function Competencies: Knowledge in relevant scientific field, required. Knowledge of research techniques or methods, required. Knowledge of regulatory policies and procedures, required. Analytical skills, required. Problem-solving skills, required. Attention to detail, required. Organizational skills, required. Verbal and written communication skills, required. Ability to work independently and as part of a team, required. Knowledge of Microsoft Office, required.

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