Ctr Applied Genomics and Precision Med
Are you a quantitative scientist with a strong interest and background in genomic medicine? The Center for Applied Genomics and Precision Medicine (CAGPM) at Duke University would like you to join our interdisciplinary team!
About this role:
As a biostatistician in CAGPM, you will work within applied genomics and precision medicine programs focusing on analysis of high-dimensional genomic and clinical datasets, including clinical survey data, pedigree data, (RNA) sequencing data, microarray data, proteomics data, multiplex PCR data or other complex 'omic' datasets. Commonly performed analyses include hypothesis testing, data normalization, clustering, testing for differential expression, principal components analysis, generalized linear model development, feature and model selection, and functional enrichment and pathway analyses.
You will apply state-of-the-art and classical statistical approaches to a variety of clinical datasets to elucidate novel biological information and clinical relevance. The specific clinical areas of interest include family health history and inherited disease risk, infectious disease, biopolymer exposures, cardiovascular events, and pharmacogenomics, with continued expansion to other clinical fields.
As a Biostatistician II in CAGPM, you will, with appropriate guidance, prepare statistical analysis plans. independently generate descriptive and basic test statistics, perform basic analysis requests and generate intermediate statistical modeling results.
The CAGPM is a highly collaborative work environment, and you will interact with physicians, biologists, and quantitative scientists within the applied genomics and precision medicine programs supporting refinement and interpretation of analytical results from biological and clinical studies and activities destined for publication. You will have opportunities for publication, both in methodological journals as well as relevant medical journals. You will assist the team in developing research results into quality manuscripts for submission to peer-reviewed journals, and may have the opportunity to present your work at relevant scientific meetings or conferences.
You will be an integral member of any team of investigators working on project(s) from which the data is derived.
Documents analyses, creates summaries, and presents results in written and verbal form to requestors. Able to work on any phase of a manuscript project, from initial meeting with an investigator to final review of a manuscript prior to submission for publication, with guidance.
Builds documentation and organizational skills to effectively return to a project after long intervals during which no progress was made by other members of the project team. Contributes meaningfully to discussions of analyses and identifies next steps for analyses.
Designs analysis data set specifications through writing own R and/or Python code, finds and corrects errors, and validates output and results. Combines multiple disparate raw databases and derives analysis variables accurately.
Collaborates effectively with statistical programmers that support projects. Identifies potential data problems from analytic queries and brings them to the attention of the team. Demonstrates understanding of project data collection processes and data sets and shares knowledge with collaborators.
Participates in most statistical aspects of a project, with consultation or assistance when needed. Represents the functional group in project team meetings and contributes constructively to project discussions. Understands the contracted scope of work and forecasts monthly hours expected to complete each project. Creates timelines for statistical project management, with assistance from project leader and statistical managers.
Drafts statistical sections for study protocols, with guidance of senior or faculty statistician. Generates project randomization sequences. Provides input regarding data collection tools and data correction criteria and procedures.
Understands study data and the intricacies of the process through which it is being collected. Handles and secures highly confidential and sensitive analyses and documentation.
Collaborates closely with investigators, sponsors, and other project leadership to ensure that project results and conclusions are presented accurately and without bias.
Participates actively in the statistical team responsible for designing and validating analysis data sets, programs, and statistical output products (tables, listings, figures). Adheres to standard operating procedures (SOPs) of the center as they apply to documentation and validation of clinical research statistics
Develops leadership and communication skills and shares them with others. Manages project responsibilities with decreasing levels of supervision or regular support and takes initiative to complete project-specific responsibilities with minimal supervision. Demonstrates progress in ability to multi-task.
2681 BIOSTATISTICIAN II
Job Family Level
Full Time / Part Time
Regular / Temporary
Duke University is an Affirmative Action/Equal Opportunity Employer committed to providing employment opportunity without regard to an individual's age, color, disability, genetic information, gender, gender identity, national origin, race, religion, sexual orientation, or veteran status.*******************************************************Essential Physical Job Functions:Certain jobs at Duke University and Duke University Health System may include essential job functions that require specific physical and/or mental abilities. Additional information and provision for requests for reasonable accommodation will be provided by each hiring department.
Work requires a minimum of a Master's degree in (bio)statistics or related field and no relevant experience, or a bachelors degree in (bio)statistics or related field and 2 years relevant experience, or an equivalent combination or relevant education and/or work experience.
OR AN EQUIVALENT COMBINATION OF RELEVANT EDUCATION AND/OR EXPERIENCE. Prior contribution to analysis of research projects, a working knowledge of SAS, and solid command of the English language is required.
Job Skill Requirements:
- Must be self driven and able to communicate effectively with collaborators in medicine and biology.
- The position will require frequent interactions with others in all phases from experimental design to paper submission. As such, exceptional written and oral communication skills are required.
- Time management skills are necessary, as there will be multiple active projects at any given time. A successful candidate will manage his/her time and prioritize importance of various projects.
Usual office working conditions
The intent of this job description is to provide a representative and level of the types of duties and responsibilities that will be required of positions given this title and shall not be construed as a declaration of the total of the specific duties and responsibilities of any particular position. Employees may be directed to perform job-related tasks other than those specifically presented in this description.
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Duke University is an Affirmative Action/Equal Opportunity Employer committed to providing employment opportunity without regard to an individual's age, color, disability, genetic information, gender, gender expression, gender identity, national origin, race, religion, sexual orientation, or veteran status.
Essential Physical Job Functions: Certain jobs at Duke University and Duke University Health System may include essential job functions that require specific physical and/or mental abilities. Additional information and provision for requests for reasonable accommodation will be provided by each hiring department.