RESEARCH INVESTIGATOR SR
Duties: The employee will devote his/her time conducting research on the area of tumor hypoxia as it relates to radiation resistance as well as the influence of immune effects on radiation response and ways of modulating both (hypoxia and immune response) in a way that favors tumor cell killing by radiation. The employee will be expected to be able to function with a significant degree of autonomy and independence, developing new areas of investigation and designing new experiments. One of the major projects in the lab is to assess the ability of toll-like receptor (TLR) agonists such as resiquimod to augment the response to radiation. The employee will also devote effort to developing breast cancer models to evaluate the effects and cell signaling modulators on breast cancer growth. Much of this work will be conducted in tumors grown in mice. Hence the employee will be expected to write/manage IACUC protocols. Employee will also be expected to have proficiency in performing in vitro laboratory techniques including cloning, gene expression, immunoblotting, qPCR, immunohistochemistry. Employee will work with the PI, research associates and students to coordinate and execute experiments in these areas including reviewing their experimental data and suggesting future experiments. A significant percentage of his/her time will be devoted to help the PI create grant proposals involving the areas listed above but also relating to breast cancer, which is a new area of investigation for the PI
Qualifications: Highly advanced professional discipline. M.D., Ph. D., or equivalent doctoral degree and 5 to 7 years of experience required.
Reference Number: 40-25331
Salary Grade: RES
Employment Type: Exempt
Org: RO-Radiation Oncology
Special Requirements: Background check required after a conditional job offer is made. Consideration of the background check will be tailored to the requirements of the job.
Job Family: I-Technical/Professional Research