RESEARCH SPECIALIST D ASSAY DEVELOPMENT
Duties: The University of Pennsylvania (UPenn) Gene Therapy Program (GTP) is a state-of-the-art facility advancing gene therapy efforts through its own basic and translational research, providing vector-related materials and services through the UPenn Vector Core, and taking therapies into the clinic with scalable production and GLP/ GMP testing in the Process Development group.
GTP's Analytics Group is currently accepting applications for a Research Specialist D position in the Assay Development Group. The candidate will execute various characterization and lot release assays to assess the potency of viral-based vectors produced in the Gene Therapy Program in support of manufacturing as well as IND-enabling, Pharmacology/Toxicology and Clinical studies. The duties include design of potency assays, report writing, training of QC personnel and thorough documentation for all activities.
The Research Specialist D will participate in writing of the SOP and BRF documents. The Research Specialist D will be responsible for training QC personnel and will present data internally and with project sponsors.
Qualifications: Master's degree and 3 to 5 years of experience or an equivalent combination of education and experience required.
Must be detail-oriented, organized, technically competent and be able to perform hands-on work in the laboratory.
Experience with cell culture and assay development is required.
Previous assay development in one or more aspects such as ELISA, enzymatic, in-cell westerns, and/or high content imaging technologies is preferred but not required.
Experience with GraphPad Prism and/or JMP is preferred but not required.
Previous development of SOP and BRF is a plus but is not required.
Must be self-motivated and highly effective in a team-based environment.
Strong oral and written communication skills are required
Reference Number: 40-25380
Salary Grade: 027
Employment Type: Exempt
Org: DM-Gene Therapy Program
Special Requirements: Background check required after a conditional job offer is made. Consideration of the background check will be tailored to the requirements of the job.
Job Family: I-Technical/Professional Research