Research Assistant 4
Title: Research Assistant 4
Department: Epidemiology and Biostatistics
Job ID: 6038
Working under a high degree of independence and under general direction, the Research Assistant 4 will coordinate multiple complex research projects of a non-routine nature in the Department of Epidemiology and Biostatistics, Case School of Medicine. The Research Assistant 4 will perform molecular biology and genetic/genomic bench and computational analysis using multiple high throughput platforms to reach the goals of various research projects, including determining the genetic/genomic basis of speech and language disorders, Eye Disorders (e.g. Fuchs Dystrophy, Age-related Macular Degeneration), and other projects. In addition, the Research Assistant 4 will assist in maintaining a comprehensive inventory of a large volume of DNA and other biological samples, equipment and reagents, working in a team atmosphere to generate new knowledge.
- Perform DNA and RNA extractions from saliva, blood, tissues and cell cultures for various downstream experiments including genotyping, RNA-seq, and exome and whole genome sequencing. Perform highly complex epigenomic experiments on various samples, instituting and implementing quality control of these complex experiments. Interpret the data/results from these experiments and co-author research projects. (40%)
- Independently read scientific papers/protocols, and provide recommendations to the principal investigator regarding significant developments on a variety of research projects, particularly development of new techniques. Create and test new or improved techniques/procedures involving a high degree of skill and training. Evaluate new analytical platforms and methods for high throughput genomic analyses. Troubleshoot experiments with a high degree of independence as needed. (25%)
- Produce data and results for NIH and other federal grants, including tables, figures and written text. Generate financial projections for lab and manage lab budgets. Keep extensive documentation of lab expenditures, and work with the admin staff in EPBIO to reconcile grant expenditures. (15%)
- Develop and maintain databases for the tracking of samples and assay results. Record laboratory results in a format that others can follow in both electronic and hard copy formats. Ensure safety of existing clinical and laboratory data, particularly following Institutional Review Board (IRB) guidelines for identifiable data and ensuring that all data are secure and remain private. Create research protocols for data collection of various samples and tissues, including working with the IRB and various co-investigators. Teach or instruct others in research techniques. (10%)
- Manage all safety protocols for the laboratory, including safe operation of a variety of scientific equipment. (5%)
- Train and manage new staff; direct the work of students. (5%)
Perform other duties as assigned that are necessary for the functioning of the laboratory and the success of the research projects.
Department: Continuous contact with supervisor, as well as other members of the laboratory and the department, to facilitate the exchange of results, ideas and techniques.
University: Contacts outside of the department includes working with core facilities frequently to achieve research objectives.
External: Maintain contact with vendors to obtain best pricing and to learn about new products. Contact with external faculty/staff and students as required by the project.
Students: Contact with graduate students.
May supervise research assistants, technicians and students. Train new staff and provide everyday oversight of the work of the research laboratory.
Experience: 5 or more years of experience in genetic, molecular biology and/or related fields. Demonstrated ability to manage other technicians. Experience with bioinformatics applications ideal.
Education/Licensing: Bachelor of Science required.
- Ability to perform PCR, run agarose gels and interpret the results.
- Must possess the following technical skills: sterile technique including cell culture, reagent and media preparation, and basic/advanced mathematical calculations.
- Must possess molecular biology skills such as; PCR, DNA and protein electrophoresis, cloning and basic sequencing knowledge.
- Ability to independently read a variety of manuals/protocols, comprehend and develop laboratory protocols.
- Good communication and interpersonal skills; ability to effectively work and communicate with various individuals within and external to the university.
- Good organization skills; ability to multi-task, prioritize and meet deadlines. Must demonstrate attention to detail and accuracy, time management, and follow-through.
- Proficient with Microsoft Windows, including Excel and Access. Ability to easily master bioinformatics techniques.
- Willingness and ability to rely on and follow instructions and pre-established guidelines to perform the functions of the job.
- Ability to work effectively, independently and collaboratively within a team.
- Must be highly motivated, conscientious and demonstrate willingness to learn new techniques, procedures, processes, and computer programs as needed.
General laboratory environment. May have exposure to the following hazards: electrical currents, airborne or contact exposure to bacterial or viral materials; general, toxic or caustic chemicals. The candidate will be working in a laboratory in the Department of Epidemiology and Biostatistics. The supervisor strives to create a safe and pleasant work environment and follows Environmental Health and Safety standards.
Occasionally willing to come in on weekends and evenings for specific projects or work from home. Serve as an emergency laboratory contact, and respond to emergency calls on an as needed basis.
In employment, as in education, Case Western Reserve University is committed to Equal Opportunity and Diversity. Women, veterans, members of underrepresented minority groups, and individuals with disabilities are encouraged to apply.
Case Western Reserve University provides reasonable accommodations to applicants with disabilities. Applicants requiring a reasonable accommodation for any part of the application and hiring process should contact the Office of Inclusion, Diversity and Equal Opportunity at 216-368-8877 to request a reasonable accommodation. Determinations as to granting reasonable accommodations for any applicant will be made on a case-by-case basis.
CWRU offers a flexible benefits package including tuition waiver for employees and dependents; Respond in confidence, including salary history : CASE WESTERN RESERVE UNIVERSITY, Human Resources Job Code #6038, apply to: jobs.case.edu