Postdoctoral Scholars - Chemical Biology, Nanotechnology, Biosensors, Protein Engineering, Biophysi
Open May 23rd, 2016 through May 19th, 2017
Department of Chemistry, May, 2016, Anticipates openings for
POSTDOCTORAL SCHOLAR POSITIONS
CHEMICAL BIOLOGY, NANOTECHNOLOGY, BIOSENSORS, PROTEIN ENGINEERING, BIOPHYSICS, AND BIOCHEMISTRY
(A) Engineering biosensors for detecting cancer biomarkers
Phage-displayed libraries are designed and selected to identify binding partners to cancer biomarkers, which are recombinantly overexpressed and purified.
(B) DNA sequencing with nanocircuits
Tethering DNA polymerase to nanometer-scale electronic circuits could enable faster, more accurate DNA sequencing, and uncover new insights into the enzymology of this key protein.
(C) Biosynthesis and enzymology
A vortex fluid device opens new frontiers in protein folding, enzymatic catalysis and biosynthesis.
Recent Ph.D. is required (2013 or later). Salary will be commensurate with experience. Please apply online at: https://recruit.ap.uci.edu/apply/JPF03426 and send a curriculum vitae, publication list and arrange for three letters of recommendation to be sent to:
Professor Gregory Weiss
Department of Chemistry, UCI
1102 Natural Sciences 2
University of California, Irvine
Irvine, CA 92697-2025
949/824-5566 (phone) 949/824-4759 (fax) http://www.gweisslab.net (website)
Pugliese, K.M., Gul, O.T., Choi, Y., Olsen, T.J., Sims, P.C., Collins, P.G.*, Weiss, G.A.* (2015). Processive incorporation of deoxynucleoside triphosphate analogs by single-molecule DNA Polymerase I (Klenow Fragment) nanocircuits. J. Amer. Chem. Soc. 137: 9587-9594. Akhterov, M.V, Choi, Y., Olsen, T.J., Sims, P.C., Iftikhar, M., Gul, O.T., Corso, B.L., Weiss, G.A.*, Collins, P.G.* (2015). Observing lysozyme closing and opening motions by high-resolution single molecule enzymology. ACS Chem. Biol.10: 1495-501. Yuan, T.Z., Ormonde, C.F.G., Kudlacek, S.T., Kunche, S., Smith, J.N., Brown, W.A., Pugliese, K.M., Olsen, T.J., Iftikhar, M., Raston, C.L.*, Weiss, G.A.* (2015). Shear stress-mediated refolding of proteins from aggregates and inclusion bodies. ChemBioChem. 16: 393-396. Widely reported in the popular and science media. Altmetric score: 713. Mohan, K., Donavan, K.C., Arter, J.A., Penner, R.M.*, Weiss, G.A.* (2013). Sub-nanomolar detection of prostate specific membrane antigen in synthetic urine by synergistic, dual ligand phage. J. Amer. Chem. Soc. 135: 7761-7767. Choi, Y., Moody, I.S., Sims, P.C., Hunt, S.R., Corso, B.L., Perez, I., Weiss, G.A.*, Collins, P.G.* (2012). Single molecule lysozyme dynamics monitored by an electronic circuit. Science. 335: 319-324. J
The University of California, Irvine is an Equal Opportunity/Affirmative Action Employer advancing inclusive excellence. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, age, protected veteran status, or other protected categories covered by the UC nondiscrimination policy.
Job location Irvine, CA
- Curriculum Vitae - Your most recently updated C.V.
- Publication list - List of publications
- Cover Letter (Optional)
- Statement of Research (Optional)
- Statement of Teaching (Optional)
- Statement of Contributions to Diversity - Statement addressing how past and/or potential contributions to diversity will advance UCI's Commitment to Inclusive Excellence. (Optional)
- Misc / Additional (Optional)
3-5 letters of reference required
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