Research Associate

Location
Boulder, CO
Posted
Feb 21, 2017
Institution Type
Four-Year Institution



A postdoctoral position is available in the Hough Lab in the BioFrontiers Institute and Department of Physics at University of Colorado-Boulder. Interviews will take place in person in Boulder on a rolling basis and the start date is flexible.

The Hough Lab works at the interface of physics and biochemistry, looking at the role of intrinsically disordered domains in protein function (http://pubs.acs.org/doi/abs/10.1021/acschembio.6b00507). In particular, this position is for a project to dissect the role of the C-terminal tail of tubulin on its function by NMR and other biophysical techniques. Of particular interest are the effects of post-translational modifications on binding, bending, and polymerization, and as well as the corresponding changes in tubulin structure and dynamics as probed by NMR. We use Tetrahymena thermophila as a source for tubulin. We will capitalize on the broad range of mutant strains with differential levels of tubulin modifications. The lab is located in the new Jennie Smoly Caruthers Biotechnology Building on East Campus.

Group website: http://www.colorado.edu/physics-biophysics/

The candidate will work with two others on a collaborative project to study the role of tubulin tail post-translational modifications. Applicants interested in either the biophysical or structural aspects of this project are both encouraged to apply. The candidate will be expected to develop and pursue independent research questions within this overall framework.




Qualifications

Degree requirements: PhD in biophysics, biochemistry, cell biology, or related field.

Minimum qualifications: Significant research accomplishments, including first-author publications in a related field. Experience and expertise in NMR, protozoa cell biology or tubulin biochemistry, or relevant expertise that will bring a unique contribution to the project. The candidate must be strongly self-motivated, responsible and collaborative.

Desired qualifications: Experience in a subset of the common methods in the lab: Nuclear Magnetic Resonance Spectroscopy (NMR), molecular cloning, protein expression and purification, bacterial and eukaryotic cell culture, time-lapse microscopy, image processing, computational analysis of data.


Special Instructions to Applicants:The University of Colorado Boulder is committed to providing a safe and productive learning, living and working community. To achieve this goal, we conduct background investigations for all final applicants being considered for employment. Background investigations include a criminal history record check, and an EPLS (Excluded Parties List System) check. The Immigration Reform and Control Act requires that verification of employment eligibility be documented for all new employees by the end of the third day of work.

The University of Colorado is an equal opportunity and affirmative action employer committed to assembling a diverse, broadly trained faculty and staff in compliance with applicable laws and in furtherance of its commitment to fostering an environment that welcomes and embraces diversity, the University of Colorado does not discriminate on the basis of race, color, creed, religion, national origin, sex (including pregnancy), disability, age, veteran status, sexual orientation, gender identity or expression, genetic information, political affiliation or political philosophy in its programs or activities, including employment, admissions, and educational programs. Inquiries may be directed to Boulder campus Title IX Coordinator by calling 303-492-2127.

Application Materials Required:Cover Letter, Resume/CV, List of References, Unofficial transcript(s), Additional Attachments - Refer to Application Materials Instructions Below

Application Materials Instructions:Interested candidates should submit as ONE PDF the following: 1. Cover letter (see details below) 2. CV including names and contact information of three references 3. Unofficial transcript The cover letter should address the following: 1) What is your relevant experiences and expertise? 2) What is your current employment (if any), and why are you looking for a new position? 3) When are you available to start a new position? 4) What are your short and long-term professional goals? 5) Describe your ideal environment and work schedule. The final candidate will be required to provide a proof of degree as part of the final hiring dossier requirement. This position is eligible for medical, dental and life insurance, retirement benefits programs, and is eligible for monthly vacation and sick leave accruals. The University of Colorado Boulder conducts background checks on all final applicants being considered for employment, prior to the issuance of an offer letter.



Job Category: Faculty

Primary Location: Boulder

Department: B0001 -- Boulder Campus - 10763 - Biofrontiers Institute

Schedule: Full-time

Posting Date: Oct 24, 2016

Closing Date: Ongoing

Posting Contact Name: Loren Hough

Posting Contact Email: loren.hough@colorado.edu

Position Number: 00612946

PI96903978