Philadelphia, Philadelphia County
Jun 21, 2016

Duties: The candidate will design and conduct independent experiments on the metabolic physiology of nuclear hormone receptors, using mouse models, cell culture models, and human tissue samples. The ideal candidate will have conducted research in gene regulation and/or epigenetics, with experience in 3 main roles. First, it involves management of a mouse colony, with extensive handling of mice, obtaining blood and tissue samples, feeding specialized diets, ordering, breeding, and genotyping. The ideal candidate will also have extensive experience in writing and editing animal protocols for IACUC. Second, the position involves performing routine laboratory management duties, such as ordering of supplies, routine equipment maintenance, and training new personnel. Third, the position involves experimental work in molecular and cellular biology, including processing cell and tissue samples to generate RNA, DNA, and protein, as well as quantitative PCR, molecular cloning, cell culture, western blots, and various biochemical assays. Other key techniques are chromatin immunoprecipitation and construction of libraries for next generation sequencing. Careful tracking and record-keeping of the mouse colony and all other experiments and samples are a must. Candidate must also be self-motivated and able to work independently with direction from an immediate supervisor.

Position is contingent on continued funding.

Qualifications: A Bachelor's Degree and 3 years to 5 years of experience or equivalent combination of education and experience is required. Lab experience, particularly mouse colony management and general lab management and ordering are strongly preferred.

Reference Number: 40-23035

Salary Grade: 026

Employment Type: Exempt

Org: DM-Endocrinology, Diabetes & Metabolism

Special Requirements: Background check required after a conditional job offer is made. Consideration of the background check will be tailored to the requirements of the job.

Job Family: I-Technical/Professional Research

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