Research Assistant Professor
Coming to work at the University of North Carolina at Chapel Hill means more than just accepting a job. You're becoming part of a rich tradition of excellence and a community of people working to make a difference.
Since the University of North Carolina at Chapel Hill's founding in 1789 as the nation's first public university, Carolina has been a place where students, faculty, staff and members of the larger community have stretched their potential and helped make the world around them a better place.
Give us a look. See what Carolina has for you and where your talents might fit well with the great team we have on campus. Together, we can make a difference for North Carolina and beyond.
The Department of Microbiology & Immunology in partnership with Lineberger Comprehensive Cancer Center and the Carolina Institute for Nanomedicine are currently looking for a Research Assistant Professor to complement our immunology team in designing and evaluating PRINT particulate vaccine formulations for cancer immunotherapy or against infectious disease in murine models.
Ph.D. degree in biology-related field with a breadth of postdoctoral research experience in biochemistry, immunology, cell biology and molecular biology.
Qualification and Experience:
The ideal candidate must have a good understanding of top-down fabrication by PRINT® technology of particles of a range of compositions with emphasis on PLGA, PEG hydrogel and proteins utilizing novel cross linking systems. A proven research and publication record is required on development, optimization, and implementation of cell-based assays to investigate the internalization and cellular trafficking of targeted and untargeted PRINT particles, and delivery of siRNA cargo with PRINT nanoparticles as therapeutics for cancer therapy. The ideal candidate must have broad knowledge on immunological mechanisms of prophylactic and therapeutic vaccines, and have experience in designing and evaluating PRINT particulate vaccine formulations for cancer immunotherapy or against infectious disease in murine models.
Strong experience in in vitro and in vivo evaluation of micro- and nano-particle constructs is required. Skills in cell culture manipulations (transfection, selection, cloning), molecular biology (DNA subcloning, transformation, etc.), protein expression/purification and conjugation chemistry, and tissue histology and immunofluorescence are required. Applicants must also have experience with flow cytometry, confocal microscopy, fluorescence spectroscopy, surface plasmon resonance, circular dichroism, TEM, and other analytical techniques. Extensive experience with multiple mouse handling techniques including various routes for particle administration, bleeding, tissue harvesting/processing and live mouse imaging is required.
The candidate must be able to work independently in planning and performing experiments, analyzing and presenting data effectively both orally and in writing. It is equally important that the ideal candidate must be willing to interact with a diverse group of people, planning and coordinating the scientific direction of graduate students and postdoctoral fellows. Experience in grant planning and writing would be a plus.
Department Contact Name: J Matthew Hawkins - HR Manager
Department Contact Telephone or Email: firstname.lastname@example.org
For complete job descriptions and to apply, visit: http://hr.unc.edu
The University of North Carolina at Chapel Hill is an Equal Opportunity Employer.