Posting Description: The Section of Genetics in the Department of Pediatrics has an opening for a full-time Research Associate to work at the Anschutz Medical Campus in Aurora. The Section of Genetics is home to a vigorous research program in genetics and metabolic diseases. The person will be involved in research and clinical studies in the neurogenetic disorders of mitochondrial glycine metabolism, in particular of nonketotic hyperglycinemia. The aim of the study is to characterize how disturbance of glycine metabolism causes brain dysfunction. The person will be involved in functional analysis of the effects of perturbed glycine metabolism in brain models such as cultured astrocytes, a knock-out mouse model of the disorder, and in brain pathology. Additional work can involve patient studies on genotype - phenotype correlations, discovery of new genetic causes, evaluation of its pathophysiology and new treatment development. The University of Colorado is the premier research university in Colorado, serving more than 30,000 undergraduate, graduate and health professions students in Denver, Aurora and online and awarding nearly 4,000 degrees each year. The renowned researchers and award-winning faculty of the University of Colorado offer more than 100 degree programs through 13 colleges and schools. In 2008 the University was awarded more than $371 million in research grants and contracts. The Anschutz Medical Campus includes over 5 million square feet of research, educational and clinical space on 227 acres. The Denver Campus is located in one of America's most vibrant urban centers, just steps from the Denver Center for Performing Arts, the LoDo District and the state capitol. On both campuses, students, staff and faculty have access to a broad array of academic, professional, community, recreational and cultural opportunities. The University of Colorado is committed to recruiting and supporting a diverse student body, faculty and administrative staff. The university strives to promote a culture of inclusiveness, respect, communication and understanding. Applications are accepted electronically at www.jobsatcu.com, refer to job posting RF00963. Review of applications will continue until the position is filled. The University of Colorado Denver is dedicated to ensuring a safe and secure environment for our faculty, staff, students and visitors. To assist in achieving that goal, we conduct background investigations for all prospective employees.
Minimum Qualifications: - PhD level in neurosciences, in biochemistry or genetics or a related field. - Experience working with brain cells in culture and with scientific investigations of brain function and biochemistry - Experience with molecular techniques - Experience in eukaryotic tissue culture
Required Competencies/Knowledge, Skills, and Abilities: - The ability to work independently within the lab - Excellent communications skills using the English language - The ability to write lab methods and scientific papers
Desired Qualifications: - Experience working on astrocytes - Experience working with mitochondrial enzymes - Experience with neurologic disorders or with inborn errors of metabolism
Campus: Anschutz Medical Campus